Babies skin is susceptible to diaper rash because of their tender and delicate skin. There are things you can do to prevent diaper rashes on babies. Check the diaper often to make sure it's dry. Don't leave her sit with wet or dirty diaper for a long period of time, this can really cause irritation on the skin. Gently wash the diaper area with warm water and a soft cloth. Rinse well and dry completely. Apply cream to protect the skin like balmex.